St. Bernard Prep AP Biology students explore cancer genetics at HudsonAlpha Institute

Published 8:18 pm Monday, March 10, 2025

Under the guidance of instructor Connie Briehn, Advanced Placement  Biology students from St. Bernard Preparatory School recently participated in an immersive, lab-based experience at HudsonAlpha Institute for Biotechnology in Huntsville, Alabama, investigating the genetics of cancer.

During the visit, students explored the genetic roots of cancer, distinguishing between hereditary and non-hereditary forms of the disease. Using the Hereditary Nonpolyposis Colorectal Cancer (HNPCC) kit, students traced a cancer-related mutation through a family, analyzed medical histories to create pedigrees and selected likely candidates for genetic testing. Employing gel electrophoresis, they identified family members carrying the cancer-linked mutation.

Beyond hands-on laboratory work, students engaged in thought-provoking discussions on the ethical challenges surrounding genetic testing and its implications. The visit also included a guided tour of HudsonAlpha’s state-of-the-art campus, providing students with insight into the cutting-edge research and innovations taking place within the field of biotechnology.

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HudsonAlpha Institute for Biotechnology, a nonprofit organization established in 2008, is dedicated to advancing genomic technology and research to address biological and medical challenges. Located in Huntsville’s Cummings Research Park — the second-largest research park in the nation — HudsonAlpha fosters collaboration among scientists, educators and entrepreneurs to drive breakthroughs in genetics, individualized medicine and sustainable energy solutions.

Students left the experience with a deeper understanding of the role genetics plays in human health and the evolving field of biotechnology. St. Bernard Prep remains committed to providing students with dynamic learning opportunities that inspire scientific curiosity and prepare them for future careers in STEM fields.

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